However, the very best defense against the joint pain is staying active. What are the new treatment options for migraines? It's important to bring up issues with your doctor even if they seem aloof about them. Amy, Everyone is different in what they are willing/able to tolerate. This does not change the effectiveness of the treatment. Study continues. But this side effect was more commonly reported in those taking the medication for advanced breast cancer. Subsequently, they took the drug tamoxifen. The names in parentheses are brand names. I am so happy for you. Will you feel better after stopping your aromatase inhibitor medication and if so, when? This medicine interferes with the production of estrogen in the body. This weight gain can be even greater when it occurs suddenly as a result of breast cancer treatment. Yes, Arimidex may cause some long-term side effects. Five years of treatment with anastrozole (Arimidex) safely and effectively prevented breast cancer recurrence in high-risk postmenopausal women at 10.9 years of follow-up, according to data from the International Breast Cancer Intervention Study II (IBIS-II) Prevention trial presented at the San Antonio Breast Cancer Symposium, held December Yes, it was approved by my doc. Side effects? Christine, what symptoms are you experiencing? Specifically, it's prescribed in some. The cancer connection is that I had 2 primary cancers (breast and endometrial) that were estrogen related. This slows the growth of tumors that require estrogen to grow. Many women worry that stopping Arimidex after five years will cause their cancer to come back; however, the International Breast Cancer Intervention Study II (IBIS-II) Prevention trial reports that: Once your treatment team has decided that you can stop taking Arimidex, you can stop it completely; you wont need to taper down the dose gradually. Similarly, seek medical attention right away if you develop symptoms of a liver condition, such as yellowing of the eyes or skin. So, keep on doing that. I too stopped taking Arimidex after five years now have enlarged fatty liver, osteopenia, debilitating fatigue, progressing weakness muscle weakness weight loss poor appetite hearing loss neck and back arthalgias, abnormal high white blood count high monocytes high MCHC and high hgb, UTI's, bladder incontinence, bone spurs, herniations etc. Withdrawal symptoms? If youre concerned about this you may find it helpful to speak to your specialist. One day last summer, when I was recuperating following my DIEP surgery, it hit me I was feeling better regarding AI side effects. Bone loss is serious. This side effect was only reported in people taking the drug for advanced breast cancer. It makes me a little mad and a little sad at the same time. If you have difficulty sleeping (insomnia), some simple things like limiting caffeine in the afternoon and evening, keeping your room dark and quiet, and going to bed and getting up at a set time each day may help. I have to admit, I've gained some weight, but I don't think it is due to the Arimidex. Coping with the side effects of anastrozole Thank you for sharing them. What are the serious side effects of Arimidex? Source: Tweet (below) from recent #ASCO21 Conference. Arimidex (anastrozole) is a medication that is used to treat breast cancer in postmenopausal women. Generally it takes four to five half-lives for a drug to be eliminated from the body, so in the case of Arimidex this would be 150 to 300 hours, or six to 12 days. This was a common side effect reported in studies of people taking Arimidex. In fact, I have been convinced on several occasions that there must be something wrong with me because I used to be able to lose weight at the drop of a hat andthis has been soooo slow given the amount of exercise and food I'm consuming. This is when part of the blood clot breaks away and travels to the lung. Taking anastrozole with or after food can help reduce nausea. I am done with aromatase inhibitors! I've done personal training, nutritional counseling, meal prepping, cardio, HIIT workouts, and my blood work is all in the green. If youre experiencing any or all of these, its not fun. Examples of mild side effects that have been reported with Arimidex for early breast cancer treatment include: Examples of mild side effects that have been reported with Arimidex for advanced or metastatic breast cancer treatment include: In most cases, these side effects should be temporary. Some people may struggle with returning to pre-treatment weight after they stop taking antidepressants. Aromasin is a brand-name prescription medication. change your treatment plan or consider using a different weight management medication Regalhank. My experience so far is my oncologist refers to me to the metabolic bone specialist, and the bone specialist refers me to the oncologist! Many side effects of Arimidex will improve within a couple of weeks of stopping Arimidex; however, some may persist long term. In addition, hepatitis has been reported in people whove used Arimidex since it became available on the market. Many people find that symptoms improve over time. Suzanne, thank you so much for your response. This usually goes away when your treatment finishes. Im starting year 6 on Aromasin-I tried every AI, this is my best tolerated-after results from Index test stated Only 5 more years girlfriend! Ouch, that hurt! Wrapping Up 2022 Looking Back, Looking Forward. Among the participants, 1,920 were randomly assigned to anastrozole for five years and 1,944 to placebo. Keep speaking up about any side effects. They can assess you and offer advice on how to manage your energy levels. Stopping smoking and doing regular weight-bearing exercise can also help keep your bones strong. The list below includes factors to consider. Im fearing hair loss/thinning might be permanent. Your breast care nurse may also be able to offer support or tell you about support services in your area. Arimidex is selective too which means that it only affects blood estradiol concentrations, and has no effect on the formation of adrenal corticosteroids or aldosterone. Although rare, its possible for Arimidex to cause cardiotoxicity or liver toxicity. If youre concerned about medications that may interact with Arimidex, talk with your doctor or pharmacist. Help this goal by becoming gradually more active and you may lose some weight and you will definitely feel better. Some people find counselling or mindfulness helpful. If your levels become too high, they may recommend that you take another medication to lower your cholesterol. Thank You !!!!! I too stopped taking Arimidex after five years now have enlarged fatty liver, osteopenia, debilitating fatigue, progressing weakness muscle weakness weight loss poor appetite hearing loss neck and back arthalgias, abnormal high white blood count high monocytes high MCHC and high hgb, UTI's, bladder incontinence, bone spurs, herniations etc. If you notice that you have hair loss or thinning during your treatment with Arimidex, talk with your doctor. ! To hear from us, please sign up below. Sorry to not be more definitive, but thats my honest answer to both parts of the question. Cardiotoxicity is damage that can occur to the heart that may affect how well it works. There are no known interactions between alcohol and Arimidex. Endocrine therapy,also known ashormonal therapy,is treatment used for many early stage breast cancers that are estrogen and/or progesterone positive. The IBIS-II Prevention trial enrolled 3,864 postmenopausal women at increased risk for developing breast cancer from 2003 to 2012. Live your life to the fullest - one day at a time. You may wish to discuss this with your treatment team or GP, or ask the pharmacist who dispenses your prescriptions if they can supply you with anastrozole from the manufacturer you feel suits you the best. Feeling well physically and mentally every day is important to me. Please discuss with YOUR oncologist. Medically reviewed by Carmen Fookes, BPharm. @smspaz59 I have been taking Anastrozol for 3months now. But the biggest indicator to whether or not someone will maintain their weight loss, Dr. Grunvald said, is if they have a . by Drugs.com. These are just a few of the side effects Arimidex may cause. Also dealing with insomnia, no hot flashes or sweats. When you stop taking your injections, your body will need to recalibrate its levels of testosterone independently. Nov. 1 I told myself it was time to fish or cut bait and I stepped up the exercise and started really thinking about food choices and writing down and measuring everything that went in my mouth. trixie1313 @trixie1313 Hi Trixie. Arimidex (anastrozole) is a prescription drug thats used to treat breast cancer. Go to the Breast Cancer Support Group. We'll see what happens. vikkr Just wonderingdid all of those symptoms occur a short time after stopping the Arimidex? You may find your side effects reduce after stopping anastrozole, for others they may continue after treatment finishes. And yes, I still have a fair number of pounds to lose, but I have made progress. Researchers say radiation treatments for breast cancer in women over the age of 65 do not appear to affect the rate of survival, The former Dancing with the Stars host shares how becoming her own advocate saved her life and why she's passionate about sharing the benefits of, New research suggests that melatonin may help lower the risk of breast cancer, slow the growth of breast cancer, and help make breast cancer. In most cases, Arimidex is taken for five years, although some women may take it for a shorter period. If you can become pregnant, you should use birth control while taking Arimidex. Examples include chest pain or shortness of breath. Your doctor will likely monitor your cholesterol levels throughout your treatment with Arimidex. What are the mild side effects of Arimidex? Updated 6 May 2020 1 answer FAQ by Drugs.com. Connect with thousands of patients and caregivers for support and answers. Healthline Media does not provide medical advice, diagnosis, or treatment. Declining an AI does not necessarily mean the ca will come back. What research-backed updates about these drugs did I miss? If you feel dizzy, avoid driving. I was Dxd with an early stage breast ca. I have heard alot of women gaining alot of weight. If you have any side effects, whether theyre listed here or not, talk to your GP or treatment team. Side effects that should resolve quickly include: Chest discomfort Dizziness Dry eyes Headache Heartburn Hot flashes Nausea Pain Sex drive If dizziness persists see your GP. Not to the extent it should be anyway. Spot the signs and symptoms of secondary breast cancer, 1. Go to the Breast Cancer Support Group. Arimidex may not be right for you if you have certain medical conditions or other factors that affect your health. Dry Eyes. Select one or more newsletters to continue. If you develop bone pain, talk with your doctor. Aromasin contains the active drug exemestane. Anastrozole can sometimes cause headaches. Osteoporosis. Ask your doctor what other medications are better options for you. 1998-2023 Mayo Foundation for Medical Education and Research. I'll cook what I want to eat and he's welcome to eat it, but he'd rather have what he likes, so he cooks for himself (and continues to gain weight). Arimidex can affect your liver and may cause increased liver enzyme levels. You stop taking antidepressants interferes with the production of estrogen in the body to lower your cholesterol levels throughout treatment. Is staying active ) is a medication that is used to treat cancer! This goal by becoming gradually more active and you may lose some will i lose weight after stopping arimidex, but have. The participants, 1,920 were randomly assigned to anastrozole for five years, although some may... This was a common side effect was more commonly reported in those taking the for. Breast and endometrial ) that were estrogen related another medication to lower cholesterol... 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will i lose weight after stopping arimidex